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Anabolic Signal Induction : Preclinical research on secondary liver IGF-1 synthesis

doi: 10.1128/JVI.00641-08 161 KemballCCAlirezaeiMFlynnCTWoodMRHarkinsSKiossesWBet al

Drug interactions are another critical consideration

29 Ligamentous instability and tears (incidence: 46/100,000 person-years 30 ), and meniscectomies (incidence: 224/100,000 31 ) further compound the high risk of progression to OA 32 and increase the likelihood of patient exclusion